The 17 papers included in this book were carefully reviewed and selected from 25 submissions. They focus on wide range of topics relevant to SASHIMI and reflect recent developments in methods for image-to-image translation, generative modelling, physics-inspired synthesis, super-resolution and image segmentation and classification.Applications include magnetic resonance imaging (MRI), computed tomography (CT), optical coherence tomography (OCT) and histopathology imaging.