Receptor - Based Drug Design

· CRC Press
E-grāmata
400
Lappuses
Piemērota
Atsauksmes un vērtējumi nav pārbaudīti. Uzzināt vairāk

Par šo e-grāmatu

Employing a wide range of examples from G-protein-coupled receptors and ligand-gated ion channels, this detailed, single-source reference illustrates the principles of pharmacological analysis and receptor classification that are the basis of rational drug design.
Explains the experimental and theoretical methods used to characterize interactions between ligands and receptors-providing the pharmacological information needed to solve treatment problems and facilitate the drug design process!
Demonstrating the achievements of the receptor-based approach in therapeutics and indicating future directions, Receptor-Based Drug Design
  • introduces novel computer-assisted strategies for the design of new agonists, antagonists, and inverse agonists for G-protein-coupled receptors
  • shows how to assess agonist concentration-effect curve data
  • discusses radioligand binding assays
  • presents new in vitro multiarray assays for G-protein-coupled receptors
  • explains the use of individual second messenger signaling responses in analyzing drug-receptor interactions
  • examines the role of electrophysiology in finding new drugs and drug targets
  • describes selectively acting b-adrenoceptor agonists and glucocorticoid steroids for asthma treatment
  • outlines the rationale for using angiotensin receptor antagonists
  • and more!
    Written by over 25 international authorities and containing nearly 1200 bibliographic citations, Receptor-Based Drug Design is a practical resource for pharmacologists, pharmacists, and pharmaceutical scientists; organic and medicinal chemists and biochemists; molecular biologists; biomedical researchers; and upper-level undergraduate and graduate students in these disciplines.
  • Novērtējiet šo e-grāmatu

    Izsakiet savu viedokli!

    Informācija lasīšanai

    Viedtālruņi un planšetdatori
    Instalējiet lietotni Google Play grāmatas Android ierīcēm un iPad planšetdatoriem/iPhone tālruņiem. Lietotne tiks automātiski sinhronizēta ar jūsu kontu un ļaus lasīt saturu tiešsaistē vai bezsaistē neatkarīgi no jūsu atrašanās vietas.
    Klēpjdatori un galddatori
    Varat klausīties pakalpojumā Google Play iegādātās audiogrāmatas, izmantojot datora tīmekļa pārlūkprogrammu.
    E-lasītāji un citas ierīces
    Lai lasītu grāmatas tādās elektroniskās tintes ierīcēs kā Kobo e-lasītāji, nepieciešams lejupielādēt failu un pārsūtīt to uz savu ierīci. Izpildiet palīdzības centrā sniegtos detalizētos norādījumus, lai pārsūtītu failus uz atbalstītiem e-lasītājiem.