QSAR: Hansch Analysis and Related Approaches

Hugo Kubinyi · Raimund Mannhold · Povl Krogsgaard-Larsen · Hendrik Timmerman

កក្កដា 2008 · John Wiley & Sons

សៀវភៅអេឡិចត្រូនិច

252

ទំព័រ

ការវាយតម្លៃ និងមតិវាយតម្លៃមិនត្រូវបានផ្ទៀងផ្ទាត់ទេ ស្វែងយល់បន្ថែម

អំពីសៀវភៅអេឡិចត្រូនិកនេះ

QSAR ist ein Akronym für 'quantitative Struktur-Wirkung- Beziehung'. Dahinter verbergen sich Methoden, die sich nichts Geringeres zum Ziel gesetzt haben, als neue Medikamente zur Behandlung bestimmter Krankheiten gezielt zu entwickeln, nämlich ausgehend von den molekularen Strukturen.
Dieses Buch war überfällig. Erstmals seit vielen Jahren werden die auf Hansch zurückgehenden und verwandte Methoden im Überblick dargestellt. Bei aller Berücksichtigung der Theorie ist diese Einführung in die Methoden der QSAR-Analyse praxisnah. Auch aktuelle Methoden der dreidimensionalen Computersimulation von Molekülstrukturen werden angesprochen.
Hugo Kubinyi ist ein führender Experte auf diesem Gebiet. Den Lesern kommt seine 20jährige Erfahrung, gesammelt an tausenden von durchgerechneten und immer wieder verbesserten Systemen und Beispielen, zugute.
Behandelt werden unter anderem: - physikochemische Parameter - quantitative Modelle - statistische Methoden - Hansch-Analyse - Free-Wilson-Analyse - 3D-Modelle

Das Buch wendet sich gleichermaßen - mit über 200 Gleichungen und 1 100 Literaturnachweisen - an Fachleute wie an alle, die sich in die Thematik einarbeiten wollen.

អំពីអ្នកនិពន្ធ

Hugo Kubinyi studied chemistry in Vienna, Austria. He earned his PhD and continued as a PostDoc at the German Cancer Research Centre in Heidelberg. In 1986 he was appointed as associate Professor of Pharmaceutical Chemistry at the University of Heidelberg. He is former Chair of the Cheminformatics and QSAR Society and IUPAC Fellow. In 2006 he received the Herman Skolnik Award. His scientific work resulted in more than 100 publications and seven books.

Raimund Mannhold is Professor for Molecular Drug Research at the University of Düsseldorf, Germany. His scientific interests lie with QSAR studies and related methods to determine and predict drug properties. He is a founding editor of the book series 'Methods and Principles in Medicinal Chemistry' and serves on the editorial boards of several journals in the field of medicinal chemistry and drug design.

វាយតម្លៃសៀវភៅអេឡិចត្រូនិកនេះ

ប្រាប់យើងអំពីការយល់ឃើញរបស់អ្នក។

អានព័ត៌មាន

ទូរសព្ទឆ្លាតវៃ និងថេប្លេត

ដំឡើងកម្មវិធី Google Play Books សម្រាប់ Android និង iPad/iPhone ។ វាធ្វើសមកាលកម្មដោយស្វ័យប្រវត្តិជាមួយគណនីរបស់អ្នក និងអនុញ្ញាតឱ្យអ្នកអានពេលមានអ៊ីនធឺណិត ឬគ្មានអ៊ីនធឺណិតនៅគ្រប់ទីកន្លែង។

កុំព្យូទ័រយួរដៃ និងកុំព្យូទ័រ

អ្នកអាចស្ដាប់សៀវភៅជាសំឡេងដែលបានទិញនៅក្នុង Google Play ដោយប្រើកម្មវិធីរុករកតាមអ៊ីនធឺណិតក្នុងកុំព្យូទ័ររបស់អ្នក។

eReaders និងឧបករណ៍ផ្សេងទៀត

ដើម្បីអាននៅលើឧបករណ៍ e-ink ដូចជាឧបករណ៍អានសៀវភៅអេឡិចត្រូនិក Kobo អ្នកនឹងត្រូវទាញយកឯកសារ ហើយផ្ទេរវាទៅឧបករណ៍របស់អ្នក។ សូមអនុវត្តតាមការណែនាំលម្អិតរបស់មជ្ឈមណ្ឌលជំនួយ ដើម្បីផ្ទេរឯកសារទៅឧបករណ៍អានសៀវភៅអេឡិចត្រូនិកដែលស្គាល់។

រាយការណ៍អំពីខ្លឹមសារខុសច្បាប់