Phytochemicals, Signal Transduction, and Neurological Disorders
iyl 2012 · Springer Science & Business Media
E-kitab
352
Səhifələr
reportReytinqlər və rəylər doğrulanmır Ətraflı Məlumat
Bu e-kitab haqqında
Phytochemicals Signal Transduction and Neurological Disorders Phytochemicals are heterogeneous group of bioactive compounds produced by plants, which are extensively researched by scientists for their health-promoting potentials in human diseases. Unlike vitamins and minerals, phytochemicals are not required for sustaining cell viability, but they play an important role in protecting tissues and cells from the harmful effects of oxidative stress and inflammation. Examples of phytochemicals include catechins, resveratrol, ginkgo biloba, curcumin, and sulfur compounds found in garlic. Although, the precise molecular mechanisms associated with beneficial effects of phytochemicals still remain the subject of intense investigations, but it is becoming increasingly evident that phytochemicals mediate their effects by counteracting, reducing, and repairing the damage caused by oxidative stress and neuroinflammation. In addition, phytochemicals also stimulate the synthesis of adaptive enzymes and proteins through the stimulation of a transcription factor called Nrf2 and induction of phase II detoxifying enzymes. Consumption of phytochemicals induces neurohormetic response that results in the expression of adaptive stress-resistance genes that are responsible for encoding antioxidant enzymes, protein chaperones, and neurotrophic factor (BDNF). Based on the stimulation of signal transduction network and adaptive stress-resistance genes, it is proposed that the use of phytochemicals from childhood to old age along with regular exercise is an important strategy for maintaining normal aging and delaying onset of age-related neurological disorders (stroke, Alzheimer disease, and Parkinson disease). Phytochemicals Signal Transduction and Neurological Disorders presents readers with cutting edge and comprehensive information not only on bioavailability, and mechanism of action of phytochemicals in the brain, but also provides the molecular mechanism associated with beneficial effects of phytochemicals in neurotraumatic (stroke, spinal cord trauma, and traumatic brain injury) and neurodegenerative (Alzheimers disease, Parkinson disease, Huntington disease, and amyotrophic lateral sclerosis) diseases.
Bu e-kitabı qiymətləndirin
Fikirlərinizi bizə deyin
Məlumat oxunur
Smartfonlar və planşetlər
Android və iPad/iPhone üçün Google Play Kitablar tətbiqini quraşdırın. Bu hesabınızla avtomatik sinxronlaşır və harada olmağınızdan asılı olmayaraq onlayn və oflayn rejimdə oxumanıza imkan yaradır.
Noutbuklar və kompüterlər
Kompüterinizin veb brauzerini istifadə etməklə Google Play'də alınmış audio kitabları dinləyə bilərsiniz.
eReader'lər və digər cihazlar
Kobo eReaders kimi e-mürəkkəb cihazlarında oxumaq üçün faylı endirməli və onu cihazınıza köçürməlisiniz. Faylları dəstəklənən eReader'lərə köçürmək üçün ətraflı Yardım Mərkəzi təlimatlarını izləyin.
