Phytochemical, antioxidant and antimicrobial activity of Aerva lanta against respiratory and urinary tract infection organisms

Prem Jose Vazhacharickal · John Joseph · Saritha S Janardhanan

2018년 5월 · Prem Jose

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In the traditional system of medicine, the plant is being used as diuretic and anthelmintic, antidiabetic, expectorant and in the treatment of lithiasis. The plant is used for arresting haemorrhage during pregnancy, burn healing, as an anti-inflammatory, headache, skin diseases to dissolve kidney and gall bladder stones. Bacterial pathogens have evolved numerous defence mechanism against antimicrobial agents hence resistance to old and newly produced drugs is on the rise. The phenomenon of antibiotic resistance exhibited by the pathogenic minor has led to the need for screening of several medicinal plants for their potential antimicrobial activity. In the present study various extracts Aerva lanata were tested against pathogens of UTI & RTI (Staphylococus aureus, Pseudomonas sp, E. coli, Klebsiella sp.) Among the organism tested Staphylococcus aureus, E. coli showed the maximum clear zone with Aqueous extract followed by the Pseudomonas sp, Klebsiella sp, phytochemical analysis revealed the presence of sterols, saponins, glycosides phenols and resins. The phytochemicals were separated by paper chromatography and identification based on Rf valves. Antioxidant array was also carried out and found to possess antioxidant potential. This study will aim the clinician to prescribe adequate treatment for urinary tract and respiratory tract infections.