Pattern Formation in Zebrafish
Lilianna Solnica-Krezel
04/2013 · Results and Problems in Cell Differentiation Livro 40 · Springer Science & Business Media
Livro eletrónico
438
Páginas
reportAs classificações e as críticas não são validadas Saiba mais
Acerca deste livro eletrónico
What makes an ideal model system to study embryonic development? The answer to this question has varied in the course of scientific quest, depending on the available experimental approaches. Yet, at the beginning of the new millennium, most of the mainstream model organisms have one feature in common, they are amenable to genetic analysis. Indeed, the genetic approach has proven remarkably effective in the dissection of complex biological phenomena, starting with the regulation of the lactose operon in Escherichia coli, the decision between the lysogenic and lytic cycles of the lambda phage and the yeast cell cycle control. The genetic screens for mutations affecting embryonic development of a fruit fly, Drosophila melanogaster, carried out by Christiane Niisslein-Volhard, Eric Wieschaus and Edward Lewis, marked the turning point in experimental approaches to embryonic development of more complex organisms. The resulting mutants facilitated identification of the key regulatory molecules, while their phenotypic classes hinted at the underlying regulatory mechanisms. This work not only provided a paradigm for genetic dissection of other developmental processes, but also inspired many budding embryologists throughout the world. Soon thereafter, George Streisinger noted that, among vertebrates, the zebrafish, Danio rerio, offered many features facilitating the dissection of nervous system development and function. Among these, transparency of the embryo, ease of husbandry, and the highly prolific nature make the zebrafish a good genetic model system.
Classifique este livro eletrónico
Dê-nos a sua opinião.
Informações de leitura
Smartphones e tablets
Instale a app Google Play Livros para Android e iPad/iPhone. A aplicação é sincronizada automaticamente com a sua conta e permite-lhe ler online ou offline, onde quer que esteja.
Portáteis e computadores
Pode ouvir audiolivros comprados no Google Play através do navegador de Internet do seu computador.
eReaders e outros dispositivos
Para ler em dispositivos e-ink, como e-readers Kobo, tem de transferir um ficheiro e movê-lo para o seu dispositivo. Siga as instruções detalhadas do Centro de Ajuda para transferir os ficheiros para os e-readers suportados.
