Pattern Formation in Zebrafish
Lilianna Solnica-Krezel
apr. 2013 · Results and Problems in Cell Differentiation Bók 40 · Springer Science & Business Media
Rafbók
438
Síður
reportEinkunnir og umsagnir eru ekki staðfestar Nánar
Um þessa rafbók
What makes an ideal model system to study embryonic development? The answer to this question has varied in the course of scientific quest, depending on the available experimental approaches. Yet, at the beginning of the new millennium, most of the mainstream model organisms have one feature in common, they are amenable to genetic analysis. Indeed, the genetic approach has proven remarkably effective in the dissection of complex biological phenomena, starting with the regulation of the lactose operon in Escherichia coli, the decision between the lysogenic and lytic cycles of the lambda phage and the yeast cell cycle control. The genetic screens for mutations affecting embryonic development of a fruit fly, Drosophila melanogaster, carried out by Christiane Niisslein-Volhard, Eric Wieschaus and Edward Lewis, marked the turning point in experimental approaches to embryonic development of more complex organisms. The resulting mutants facilitated identification of the key regulatory molecules, while their phenotypic classes hinted at the underlying regulatory mechanisms. This work not only provided a paradigm for genetic dissection of other developmental processes, but also inspired many budding embryologists throughout the world. Soon thereafter, George Streisinger noted that, among vertebrates, the zebrafish, Danio rerio, offered many features facilitating the dissection of nervous system development and function. Among these, transparency of the embryo, ease of husbandry, and the highly prolific nature make the zebrafish a good genetic model system.
Gefa þessari rafbók einkunn.
Segðu okkur hvað þér finnst.
Upplýsingar um lestur
Snjallsímar og spjaldtölvur
Settu upp forritið Google Play Books fyrir Android og iPad/iPhone. Það samstillist sjálfkrafa við reikninginn þinn og gerir þér kleift að lesa með eða án nettengingar hvar sem þú ert.
Fartölvur og tölvur
Hægt er að hlusta á hljóðbækur sem keyptar eru í Google Play í vafranum í tölvunni.
Lesbretti og önnur tæki
Til að lesa af lesbrettum eins og Kobo-lesbrettum þarftu að hlaða niður skrá og flytja hana yfir í tækið þitt. Fylgdu nákvæmum leiðbeiningum hjálparmiðstöðvar til að flytja skrár yfir í studd lesbretti.
