Nutrition, Exercise and Epigenetics: Ageing Interventions

ยท Healthy Ageing and Longevity ืกืคืจ 2 ยท Springer
ืกืคืจ ื“ื™ื’ื™ื˜ืœื™
278
ื“ืคื™ื
ื”ื‘ื™ืงื•ืจื•ืช ื•ื”ื“ื™ืจื•ื’ื™ื ืœื ืžืื•ืžืชื™ืย ืžื™ื“ืข ื ื•ืกืฃ

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This book focuses on the three most important aspects of ageing research: nutrition, physical exercise and epigenetics. The contributors discuss ways that age-related epigenetic imprints such as DNA methylation and histone acetylation are modified by these two interventions. The emphasis on epigenetics helps to illuminate the underlying mechanisms of anti-ageing interventions, as ageing and disease are predominately epigenetic phenomena.

Among the highlights are chapter-length discussion of such topics as: how anti-inflammatory action of calorie restriction underlies the retardation of ageing and age-related diseases (Chapter 3); epigenetic modification of gene expression by exercise (Chapter 5); the role of functional foods and their bioactive components in bone health (Chapter 8); and an account of the first decade of a study of calorie restriction in nonhuman primates, conducted by the National Institute on Ageing.

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