This monograph is the second edition in the series, providing the reader with a selection of high-quality papers dedicated to current progress, new developments and research trends in man-machine interactions area. In particular, the topical subdivisions of this volume include human-computer interfaces, robot control and navigation systems, bio-data analysis and mining, pattern recognition for medical applications, sound, text and image processing, design and decision support, rough and fuzzy systems, crisp and fuzzy clustering, prediction and regression, algorithms and optimisation, and data management systems.