Peptide Nucleic Acid: Advances in Molecular Engineering and Nanostructure Design

Peptide nucleic acid-This chapter delves into the structure and properties of peptide nucleic acids, which are crucial for advancing genetic engineering techniques

MRNA display-A vital topic that explores how mRNA display technologies aid in protein selection and drug discovery, showcasing the power of peptide nucleic acids

RNA world-Examines the hypothesis of RNA as the origin of life, and its relevance to DNA nanotechnology, shedding light on the molecular mechanisms

XIST-Discusses the XIST RNA and its significant role in Xchromosome inactivation, an essential process for understanding genetic regulation

Nucleic acid-A detailed exploration of nucleic acids, their structure, function, and importance in the context of modern nanotechnology

Intracellular delivery-Focuses on innovative methods for delivering peptide nucleic acids inside cells, crucial for gene therapy and nanomedicine

Oligonucleotide-This chapter covers oligonucleotides and their use in DNA sequencing and synthesis, key tools for advancing genetic research

Morpholino-Discusses morpholino oligonucleotides, which are vital for gene expression studies and therapeutic applications in molecular biology

Locked nucleic acid-Locked nucleic acids are pivotal for the stabilization of nucleic acid structures, offering a breakthrough in the development of genebased therapies

Polyelectrolyte theory of the gene-Explores the polyelectrolyte theory and its implications for understanding gene behavior at the molecular level

Diamino acid-Provides an insight into diamino acids and their role in the design of peptide nucleic acids and their applications in synthetic biology

Nucleic acid secondary structure-An indepth examination of how nucleic acids fold into secondary structures, influencing their biological activity and therapeutic potential

Nucleic acid analogue-This chapter looks at nucleic acid analogues and how they provide new tools for genetic manipulation and molecular diagnostics

Sequencecontrolled polymer-Focuses on the design and synthesis of sequencecontrolled polymers, which have significant potential in the creation of custom molecules for DNA nanotechnology

Threose nucleic acid-A detailed discussion on threose nucleic acid, a novel synthetic polymer that mimics the structure and function of natural nucleic acids

Ribozyme-Explores ribozymes—RNA molecules with enzymatic functions—crucial for understanding the potential applications of RNA in gene therapy and diagnostics

Cellpenetrating peptide-Covers the role of cellpenetrating peptides in drug delivery, highlighting their significance in advancing nanomedicine and gene therapy

Triplestranded DNA-Investigates the formation of triplestranded DNA, an important concept for developing more efficient gene therapies

Systematic evolution of ligands by exponential enrichment-This chapter explains SELEX, a revolutionary technique for identifying ligands, pivotal in drug discovery and biotechnology

Aptamer-Discusses aptamers, their role as molecular recognition elements, and their application in drug delivery and diagnostics

Xeno nucleic acid-Focuses on the study of xeno nucleic acids, synthetic nucleic acid analogues with applications in biomolecular recognition and nanotechnology