Epigenetic Mechanisms in Cancer

Sabita Saldanha

nov. de 2017 · Translational Epigenetics Libro 3 · Academic Press

Libro electrónico

392

Páxinas

Apto

As valoracións e as recensións non están verificadas Máis información

Acerca deste libro electrónico

Epigenetic Mechanisms in Cancer provides a comprehensive analysis of epigenetic signatures that govern disease development, progression and metastasis. Epigenetic signatures dictating tumor etiologies present an opportunity for biomarker identification which has broad potential for improving diagnosis, prognosis, prediction, and risk assessment. This volumes offers a unique evaluation of signature differences in childhood, sex-specific and race-specific cancers, and in doing so broadly illuminates the scope of epigenetic biomarkers in clinical environments. Chapters detail the major epigenetic process in humans consisting of DNA methylation, histone modifications and microRNAs (miRNAs) involved in the initiation, progression and metastasis of tumors. Also delineated are recent technologies such as next generation sequencing that are used to identify epigenetic profiles (primarily methylation analysis) in samples (normal, benign and cancerous) and which are highly important to the analysis of epigenetic outcomes. - Offers broad coverage that is applicable to audiences in various area of cancer research - population studies, diagnostics, prognosis, prediction, therapy, risk, etc. - Provides critical review analysis of the topics that will clarify and delineate the potential roles of epigenetic signatures in cancer management - Covers basic, as well as, clinical areas of epigenetic mechanisms in tumorigenesis - Features contributions by leading experts in the field - Provides comprehensive coverage of current epigenetic signatures involved in the etiology of various cancers and miRNAs

Acerca do autor

Dr. Saldanha is an Assistant Professor in the Department of Biological Sciences at Alabama State University. Her current research project includes the therapeutic role of histone deacetylase inhibitors in colon and prostate cancers, and her areas of epigenetic interest include epigenetic markers as effective tools in cancer diagnosis. She has more than fifteen years of research experience in cancer epigenetics, protein biochemistry, molecular biology and cloning. She has twelve years of teaching experience and has been a STEM faculty mentor, MARC mentor, and Honor’s program project director at ASU. Recently, Dr. Saldanha was named the 2015 National Academies Education Fellow in Life Sciences. She is also currently a Health Disparities Research and Training Program Scholar at UAB and a member of the Cancer Biology Research and Training program at ASU, which was established in 2015. She serves as senior personnel for the ASU-UAB Comprehensive Cancer Center partnership and has been instrumental in developing a cancer biology course at ASU.

Valora este libro electrónico

Dános a túa opinión.

Información de lectura

Smartphones e tabletas

Instala a aplicación Google Play Libros para Android e iPad/iPhone. Sincronízase automaticamente coa túa conta e permíteche ler contido en liña ou sen conexión desde calquera lugar.

Portátiles e ordenadores de escritorio

Podes escoitar os audiolibros comprados en Google Play a través do navegador web do ordenador.

Lectores de libros electrónicos e outros dispositivos

Para ler contido en dispositivos de tinta electrónica, como os lectores de libros electrónicos Kobo, é necesario descargar un ficheiro e transferilo ao dispositivo. Sigue as instrucións detalladas do Centro de Axuda para transferir ficheiros a lectores electrónicos admitidos.

Denunciar contido ilegal