Cardiovascular Pharmacogenetics

· Handbook of Experimental Pharmacology 160. књига · Springer Science & Business Media
5,0
1 Ρ€Π΅Ρ†Π΅Π½Π·ΠΈΡ˜Π°
Π•-књига
407
Π‘Ρ‚Ρ€Π°Π½ΠΈΡ†Π°
ΠžΡ†Π΅Π½Π΅ ΠΈ Ρ€Π΅Ρ†Π΅Π½Π·ΠΈΡ˜Π΅ нису Π²Π΅Ρ€ΠΈΡ„ΠΈΠΊΠΎΠ²Π°Π½Π΅ Β Π‘Π°Π·Π½Π°Ρ˜Ρ‚Π΅ вишС

О овој С-књизи

The Human Genome Project was sold to the general public largely on the basis that a complete picture of the structure of human DNA would lead to new and better medicines. These medicines would be better because they would be tailored to individual patients, maximising the chances of a therapeutic response and mi nimising the risks of an adverse event. Taking the idea further, pundits have pre dicted that the time will come when we could carry our DNA on a card which could be read rapidly and enable the physician to choose the best drug. This is the future. This is pharmacogenetics. When the draft human DNA sequence was announced and scientists were as ked how this would help drug development, the example most frequently given was the debrisoquine model - where poor metabolisers of this hypotensive agent are exposed to higher plasma levels from a standard dose and at risk of collapse from excessive hypotension. This observation was made over 20 years ago and predated designs to sequence the human genome. Nonetheless, it raised aware ness of variation in drug metabolism and was correctly assigned to genetic poly morphisms affecting CYP2D6. Together with the discovery of pseudocholinestera se deficiency, it marked the birth of pharmacogenetics. The debrisoquine example is an interesting one and worthy of further analysis.

ΠžΡ†Π΅Π½Π΅ ΠΈ Ρ€Π΅Ρ†Π΅Π½Π·ΠΈΡ˜Π΅

5,0
1 Ρ€Π΅Ρ†Π΅Π½Π·ΠΈΡ˜Π°

ΠžΡ†Π΅Π½ΠΈΡ‚Π΅ ΠΎΠ²Ρƒ Π΅-ΠΊΡšΠΈΠ³Ρƒ

ΠˆΠ°Π²ΠΈΡ‚Π΅ Π½Π°ΠΌ својС ΠΌΠΈΡˆΡ™Π΅ΡšΠ΅.

Π˜Π½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΡ˜Π΅ ΠΎ Ρ‡ΠΈΡ‚Π°ΡšΡƒ

ΠŸΠ°ΠΌΠ΅Ρ‚Π½ΠΈ Ρ‚Π΅Π»Π΅Ρ„ΠΎΠ½ΠΈ ΠΈ Ρ‚Π°Π±Π»Π΅Ρ‚ΠΈ
Π˜Π½ΡΡ‚Π°Π»ΠΈΡ€Π°Ρ˜Ρ‚Π΅ Π°ΠΏΠ»ΠΈΠΊΠ°Ρ†ΠΈΡ˜Ρƒ Google Play књигС Π·Π° Android ΠΈ iPad/iPhone. Аутоматски сС ΡΠΈΠ½Ρ…Ρ€ΠΎΠ½ΠΈΠ·ΡƒΡ˜Π΅ са Π½Π°Π»ΠΎΠ³ΠΎΠΌ ΠΈ ΠΎΠΌΠΎΠ³ΡƒΡ›Π°Π²Π° Π²Π°ΠΌ Π΄Π° Ρ‡ΠΈΡ‚Π°Ρ‚Π΅ онлајн ΠΈ ΠΎΡ„Π»Π°Ρ˜Π½ Π³Π΄Π΅ Π³ΠΎΠ΄ Π΄Π° сС Π½Π°Π»Π°Π·ΠΈΡ‚Π΅.
Π›Π°ΠΏΡ‚ΠΎΠΏΠΎΠ²ΠΈ ΠΈ Ρ€Π°Ρ‡ΡƒΠ½Π°Ρ€ΠΈ
ΠœΠΎΠΆΠ΅Ρ‚Π΅ Π΄Π° ΡΠ»ΡƒΡˆΠ°Ρ‚Π΅ Π°ΡƒΠ΄ΠΈΠΎ-књигС ΠΊΡƒΠΏΡ™Π΅Π½Π΅ Π½Π° Google Play-Ρƒ ΠΏΠΎΠΌΠΎΡ›Ρƒ Π²Π΅Π±-ΠΏΡ€Π΅Π³Π»Π΅Π΄Π°Ρ‡Π° Π½Π° Ρ€Π°Ρ‡ΡƒΠ½Π°Ρ€Ρƒ.
Π•-Ρ‡ΠΈΡ‚Π°Ρ‡ΠΈ ΠΈ Π΄Ρ€ΡƒΠ³ΠΈ ΡƒΡ€Π΅Ρ’Π°Ρ˜ΠΈ
Π”Π° бистС Ρ‡ΠΈΡ‚Π°Π»ΠΈ Π½Π° ΡƒΡ€Π΅Ρ’Π°Ρ˜ΠΈΠΌΠ° којС користС Π΅-мастило, ΠΊΠ°ΠΎ ΡˆΡ‚ΠΎ су Kobo Π΅-Ρ‡ΠΈΡ‚Π°Ρ‡ΠΈ, Ρ‚Ρ€Π΅Π±Π° Π΄Π° ΠΏΡ€Π΅ΡƒΠ·ΠΌΠ΅Ρ‚Π΅ Ρ„Π°Ρ˜Π» ΠΈ прСнСсСтС Π³Π° Π½Π° ΡƒΡ€Π΅Ρ’Π°Ρ˜. ΠŸΡ€Π°Ρ‚ΠΈΡ‚Π΅ Π΄Π΅Ρ‚Π°Ρ™Π½Π° упутства ΠΈΠ· Ρ†Π΅Π½Ρ‚Ρ€Π° Π·Π° ΠΏΠΎΠΌΠΎΡ› Π΄Π° бистС ΠΏΡ€Π΅Π½Π΅Π»ΠΈ Ρ„Π°Ρ˜Π»ΠΎΠ²Π΅ Ρƒ ΠΏΠΎΠ΄Ρ€ΠΆΠ°Π½Π΅ Π΅-Ρ‡ΠΈΡ‚Π°Ρ‡Π΅.