Cancer Cell Chemoresistance And Chemosensitization
Ajaikumar B Kunnumakkara · Devivasha Bordoloi · Javadi Monisha
2018. g. febr. · World Scientific
5,0star
1 atsauksmereport
E-grāmata
684
Lappuses
family_home
Piemērota
info
reportAtsauksmes un vērtējumi nav pārbaudīti. Uzzināt vairāk
Par šo e-grāmatu
Despite the significant advances in cancer therapy made through constant evaluation and analysis of treatment aftereffects, the disease still remains one of the foremost causes of mortality worldwide killing more than 12 million people annually. The prime reason behind the failure of conventional chemotherapeutics which are used as the chief regimen in the comprehensive treatment of cancers is the development of chemoresistance. It can be either intrinsic or acquired and is primarily mediated via different key regulators like MDR, MAPK, NF-κB, PI3K/Akt, Wnt signaling pathways etc. Thus, agents which can target these regulatory elements or pathways and in turn sensitize cancer cells to chemotherapy holds immense prospect. However, there is barely such comprehensive work available in scientific literature that explains how chemosensitization of cancer cells functions using different drug combinations and exhibit synergism. This book provides a detailed description of chemoresistance and chemosensitization, targets for chemosensitization and various approaches adapted in the process of chemosensitization. Furthermore, the book explicates the role of various chemosensitizers, both natural and synthetic in sensitizing cancer cells and also details the current research findings on chemosensitization of different cancer types in both pre-clinical and clinical settings.
Vērtējumi un atsauksmes
5,0
1 atsauksme
Novērtējiet šo e-grāmatu
Izsakiet savu viedokli!
Informācija lasīšanai
Viedtālruņi un planšetdatori
Instalējiet lietotni Google Play grāmatas Android ierīcēm un iPad planšetdatoriem/iPhone tālruņiem. Lietotne tiks automātiski sinhronizēta ar jūsu kontu un ļaus lasīt saturu tiešsaistē vai bezsaistē neatkarīgi no jūsu atrašanās vietas.
Klēpjdatori un galddatori
Varat klausīties pakalpojumā Google Play iegādātās audiogrāmatas, izmantojot datora tīmekļa pārlūkprogrammu.
E-lasītāji un citas ierīces
Lai lasītu grāmatas tādās elektroniskās tintes ierīcēs kā Kobo e-lasītāji, nepieciešams lejupielādēt failu un pārsūtīt to uz savu ierīci. Izpildiet palīdzības centrā sniegtos detalizētos norādījumus, lai pārsūtītu failus uz atbalstītiem e-lasītājiem.
