Biomedical Aspects of Histamine: Current Perspectives

¡ ¡ ¡
¡ Springer Science & Business Media
ā§Ģ.ā§Ļ
ā§§ āϟāĻž āĻĒā§°ā§āϝāĻžāϞ⧋āϚāύāĻž
āχāĻŦ⧁āĻ•
441
āĻĒ⧃āĻˇā§āĻ āĻž
āĻŽā§‚āĻ˛ā§āϝāĻžāĻ‚āĻ•āύ āφ⧰⧁ āĻĒā§°ā§āϝāĻžāϞ⧋āϚāύāĻž āϏāĻ¤ā§āϝāĻžāĻĒāύ āϕ⧰āĻž āĻšā§‹ā§ąāĻž āύāĻžāχ  āĻ…āϧāĻŋāĻ• āϜāĻžāύāĻ•

āĻāχ āχāĻŦ⧁āĻ•āĻ–āύ⧰ āĻŦāĻŋāĻˇā§Ÿā§‡

Since its identification by Sir Henry H. Dale a century ago, histamine has become one of the most important multifunctional biogenic amines in the field of biomedicine. The pharmacological effects of histamine are mediated through four types of membrane histamine receptors; H1R, H2R, H3R and H4R, which are all heptahelical G-protein-coupled receptors. It has been known to play the broadest spectrum of activities in various physiological and pathological conditions including cell proliferation, differentiation, hematopoiesis, embryonic development, regeneration, wound healing, aminergic neurotransmission and numerous brain functions, secretion of pituitary hormones, regulation of gastrointestinal and circulatory functions, cardiovascular system, as well as inflammatory reactions, modulation of the immune response, endocrine function and homeostasis, and other important areas.

This book is a compendium of the current state of established and investigational literature on Histamine, its receptors and their Agonists and antagonists. It provides a comprehensive overview of histamine biology in the field of biochemistry, cell biology, molecular biology, immunology, allergy, neurobiology, pharmacology, microbiology and reproductive biology. The first section on Histamine biology and physiology leads into subsequent sections on enzymology, pharmacology, regulation of the immune system and cell proliferation and role in allergic and other diseases including acid peptic diseases, inflammatory diseases, autoimmune and cancer diseases, nervous system, reproductive functions and hematopoiesis. The compilation of chapters in the book presents the most recent advances in histamine research and bridges the basic and clinical aspects of histamine biology.

āĻŽā§‚āĻ˛ā§āϝāĻžāĻ‚āĻ•āύ āφ⧰⧁ āĻĒā§°ā§āϝāĻžāϞ⧋āϚāύāĻžāϏāĻŽā§‚āĻš

ā§Ģ.ā§Ļ
ā§§ āϟāĻž āĻĒā§°ā§āϝāĻžāϞ⧋āϚāύāĻž

āĻāχ āχāĻŦ⧁āĻ•āĻ–āύāĻ• āĻŽā§‚āĻ˛ā§āϝāĻžāĻ‚āĻ•āύ āϕ⧰āĻ•

āφāĻŽāĻžāĻ• āφāĻĒā§‹āύāĻžā§° āĻŽāϤāĻžāĻŽāϤ āϜāύāĻžāĻ“āĻ•āĨ¤

āĻĒāĻĸāĻŧāĻžā§° āύāĻŋāĻ°ā§āĻĻ⧇āĻļāĻžā§ąāϞ⧀

āĻ¸ā§āĻŽāĻžā§°ā§āϟāĻĢ’āύ āφ⧰⧁ āĻŸā§‡āĻŦāϞ⧇āϟ
Android āφ⧰⧁ iPad/iPhoneā§° āĻŦāĻžāĻŦ⧇ Google Play Books āĻāĻĒāĻŸā§‹ āχāύāĻˇā§āϟāϞ āϕ⧰āĻ•āĨ¤ āχ āĻ¸ā§āĻŦāϝāĻŧāĻ‚āĻ•ā§āϰāĻŋāϝāĻŧāĻ­āĻžā§ąā§‡ āφāĻĒā§‹āύāĻžā§° āĻāĻ•āĻžāωāĻŖā§āϟ⧰ āϏ⧈āϤ⧇ āĻ›āĻŋāĻ‚āĻ• āĻšāϝāĻŧ āφ⧰⧁ āφāĻĒ⧁āύāĻŋ āϝ'āϤ⧇ āύāĻžāĻĨāĻžāĻ•āĻ• āϤ'āϤ⧇āχ āϕ⧋āύ⧋ āĻ…āĻĄāĻŋāĻ…'āĻŦ⧁āĻ• āĻ…āύāϞāĻžāχāύ āĻŦāĻž āĻ…āĻĢāϞāĻžāχāύāϤ āĻļ⧁āύāĻŋāĻŦāϞ⧈ āϏ⧁āĻŦāĻŋāϧāĻž āĻĻāĻŋāϝāĻŧ⧇āĨ¤
āϞ⧇āĻĒāϟāĻĒ āφ⧰⧁ āĻ•āĻŽā§āĻĒāĻŋāωāϟāĻžā§°
āφāĻĒ⧁āύāĻŋ āĻ•āĻŽā§āĻĒāĻŋāωāϟāĻžā§°ā§° ā§ąā§‡āĻŦ āĻŦā§āϰāĻžāωāϜāĻžā§° āĻŦā§āĻ¯ā§ąāĻšāĻžā§° āϕ⧰āĻŋ Google PlayāϤ āĻ•āĻŋāύāĻž āĻ…āĻĄāĻŋāĻ…'āĻŦ⧁āĻ•āϏāĻŽā§‚āĻš āĻļ⧁āύāĻŋāĻŦ āĻĒāĻžā§°ā§‡āĨ¤
āχ-ā§°ā§€āĻĄāĻžā§° āφ⧰⧁ āĻ…āĻ¨ā§āϝ āĻĄāĻŋāĻ­āĻžāχāϚ
Kobo eReadersā§° āĻĻ⧰⧇ āχ-āϚāĻŋ⧟āĻžāρāĻšā§€ā§° āĻĄāĻŋāĻ­āĻžāχāϚāϏāĻŽā§‚āĻšāϤ āĻĒā§āĻŋāĻŦāϞ⧈, āφāĻĒ⧁āύāĻŋ āĻāϟāĻž āĻĢāĻžāχāϞ āĻĄāĻžāωāύāĻ˛â€™āĻĄ āϕ⧰āĻŋ āϏ⧇āχāĻŸā§‹ āφāĻĒā§‹āύāĻžā§° āĻĄāĻŋāĻ­āĻžāχāϚāϞ⧈ āĻ¸ā§āĻĨāĻžāύāĻžāĻ¨ā§āϤ⧰āĻŖ āϕ⧰āĻŋāĻŦ āϞāĻžāĻ—āĻŋāĻŦāĨ¤ āϏāĻŽā§°ā§āĻĨāĻŋāϤ āχ-ā§°āĻŋāĻĄāĻžā§°āϞ⧈ āĻĢāĻžāχāϞāĻŸā§‹ āϕ⧇āύ⧇āĻ•ā§ˆ āĻ¸ā§āĻĨāĻžāύāĻžāĻ¨ā§āϤ⧰ āϕ⧰āĻŋāĻŦ āϜāĻžāύāĻŋāĻŦāϞ⧈ āϏāĻšāĻžāϝāĻŧ āϕ⧇āĻ¨ā§āĻĻā§ā§°āϤ āĻĨāĻ•āĻž āϏāĻŦāĻŋāĻļ⧇āώ āύāĻŋā§°ā§āĻĻ⧇āĻļāĻžā§ąāϞ⧀ āϚāĻžāĻ“āĻ•āĨ¤