Targeted Nanotechnology: Enhancing the Efficacy of Natural Anticancer drug Therapies

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· CRC Press
Ebook
356
Pages
Eligible
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About this ebook

This book examines the role of nanotechnology in advancing cancer treatment, focusing on phytochemicals derived from natural sources and their therapeutic delivery through nanotechnology. The initial chapters provide an overview of cellular and molecular mechanisms of cancer and present both passive and active targeting strategies to enhance the effectiveness of phytochemical-loaded nanosystems. The chapters also explore the nano-delivery systems tailored for potent anticancer agents such as camptothecin, berberine, paclitaxel, and many more. These molecules improve the bioavailability, stability, and efficacy of these bioactive compounds, addressing the latest innovations for agents like hesperidin, thymoquinone, epigallocatechin gallate, quercetin, and curcumin. The book also investigates the co-delivery of natural and conventional anticancer drugs, exploring potential synergies in cancer therapy. In addition, the chapters focus on nano-delivery systems for essential oils, carotenoids, and phytomolecules targeting drug-resistant cancer cells, and the role of natural compounds in cancer prevention.

Key Features:

  • Provides foundational insights into the cellular and molecular mechanisms of cancer
  • Explores innovative nano-delivery systems for natural anticancer agents from phytoconstituents
  • Discusses passive and active targeting strategies for phytochemical-loaded nanosystems
  • Highlights the therapeutic potential of nano-formulations for various natural compounds
  • Examines co-delivery of natural and synthetic anticancer drugs for improved efficacy

This book is useful for researchers and students in oncology, nanotechnology, and pharmaceutical sciences.

About the author

Anindita Behera is associated with Amity Institute of Pharmacy, Amity University, Kolkata, in the Department of Pharmaceutical Chemistry as Professor. She earned her master's degree from Pune University, India, and completed her PhD at Siksha 'O' Anusandhan Deemed to be University. Dr. Behera has developed innovative analytical methods for drug formulations used in AIDS treatment and is currently engaged in green synthesis of nanomaterials targeting various life-threatening diseases. With over 18 years of experience in research and academia, she has published numerous research and review articles in peer-reviewed journals. She has also contributed chapters to books published by major international publishers and has authored two books. Dr. Behera has guided three PhD scholars, sixteen postgraduate students, and forty-five undergraduate students in their research pursuits.

Santwana Padhi serves as Scientific Communication Manager at Publication Practice Counsel, USA. She holds a PhD in Pharmaceutics from Jamia Hamdard University, specializing in cancer nanotherapeutics. Her research focuses on preclinical and clinical investigations of drug-loaded targeted nanosystems designed to enhance solid tumor treatment. Before her doctoral studies, she gained hands-on experience as a Research Assistant at the National Institute of Immunology (NII), honing her skills in formulation science. Following her PhD, she worked as a Medical Science Liaison (MSL) at Biocon, contributing to advancements in oncology and dermatology. Later, she joined the KIIT-Technology Business Incubator as Scientific Officer, where she played a key role in supporting entrepreneurial initiatives among young researchers and securing funding for technology development and commercialization. As a Senior Medical Writer at Reseapro Scientific Services, she has contributed to more than 50 publications, medical communication materials, and regulatory documents. Additionally, she has co-edited one book published by Springer Nature. Dr. Padhi has received numerous accolades, including the Senior Research Fellowship (SRF) from ICMR, Junior Research Fellowship (JRF) from DBT, and the Award of Excellence for Scientific Contribution from Jamia Hamdard University for two consecutive years.

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