Analysis of Pharmaceuticals by Capillary Electrophoresis
Kevin D. Altria
pri 2013 · CHROMATOGRAPHIA CE-Series Libri 2 · Springer Science & Business Media
Libër elektronik
285
Faqe
reportVlerësimet dhe komentet nuk janë të verifikuara Mëso më shumë
Rreth këtij libri elektronik
During the 1980's the analysis of pharmaceuticals was dominated by the use of High Perfor mance Liquid Chromatography (HPLC). Other separative techniques such as Gas Chromato graphy and Thin Layer Chromatography offered alternatives but their quantitative capabili ties and/or solute range could not approach that of HPLC. The majority of pharmaceuticals are ionic and it would be reasonable to assume that electrophoresis may be useful in the analysis of pharmaceuticals. However, the electrophore tic instruments available in the 1980's were labour intensive and employed post-separation detection procedures. During the late 1980's and early 1990's extensive research was con ducted into the possibilities of conducting electrophoretic separations in capillaries. This approach allowed on-line detection and could be performed on fully automated equipment. This research led to the advent of modern day capillary electrophoresis (CE) instruments which offer similar performance and automation levels to that of HPLC. Research was also focused on developing applications for CE and particular attention was paid to applications within the pharmaceutical analysis area. These applications proved that CE could be applied to a wide range of drug types including water insoluble and neutral compounds. The ability to achieve efficient chiral separations of drugs also increased the popularity of the technique. CE with indirect UV detection has become established as a simple and effective alternative to ion-exchange chromatography for the determination of small inorganic or organic ions.
Rreth autorit
Dr. Kevin D. Altria ist Wissenschaftler bei der Glaxo Company in Großbritannien.
The author, Dr. Kevin D. Altria, has been working in Glaxo Wellcome R & D for 10 years. During this time he has developed and implemented many routine pharmaceutical analysis CE methods.
The author, Dr. Kevin D. Altria, has been working in Glaxo Wellcome R & D for 10 years. During this time he has developed and implemented many routine pharmaceutical analysis CE methods.
Vlerëso këtë libër elektronik
Na trego se çfarë mendon.
Informacione për leximin
Telefona inteligjentë dhe tabletë
Instalo aplikacionin "Librat e Google Play" për Android dhe iPad/iPhone. Ai sinkronizohet automatikisht me llogarinë tënde dhe të lejon të lexosh online dhe offline kudo që të ndodhesh.
Laptopë dhe kompjuterë
Mund të dëgjosh librat me audio të blerë në Google Play duke përdorur shfletuesin e uebit të kompjuterit.
Lexuesit elektronikë dhe pajisjet e tjera
Për të lexuar në pajisjet me bojë elektronike si p.sh. lexuesit e librave elektronikë Kobo, do të të duhet të shkarkosh një skedar dhe ta transferosh atë te pajisja jote. Ndiq udhëzimet e detajuara në Qendrën e ndihmës për të transferuar skedarët te lexuesit e mbështetur të librave elektronikë.
