Structural Bioinformatics: Molecular Insights into Biomacromolecular Structures and Interactions

Unlock the power of Structural Bioinformatics—a crucial field in Molecular Biophysics that bridges computational analysis with biological insights. This book provides a comprehensive guide to understanding protein structures, molecular interactions, and computational tools that shape modern biology and drug discovery. Essential for students, researchers, and professionals, it offers a deep dive into this dynamic field.

Chapters Brief Overview:

1: Structural bioinformatics – An introduction to computational methods for analyzing biomolecular structures.

2: Bioinformatics – Explores algorithms and databases that drive biological research and discoveries.

3: Protein – Examines protein structures, functions, and their role in biological processes.

4: Structural biology – Discusses techniques for determining molecular structures at atomic resolution.

5: Protein Data Bank – Highlights the importance of global repositories for protein structural data.

6: Protein structure prediction – Covers computational models for predicting unknown protein structures.

7: Structural alignment – Analyzes methods for comparing molecular conformations and evolutionary relationships.

8: Protein–protein interaction – Investigates how proteins interact and regulate cellular functions.

9: Macromolecular docking – Explains techniques for predicting molecular binding and interactions.

10: Internal Coordinate Mechanics – Introduces coordinatebased modeling of biomolecular movements.

11: Root mean square deviation of atomic positions – Evaluates structural similarities in biomolecules.

12: Biomolecular structure – Studies molecular architecture and its implications in biological systems.

13: Molecular biophysics – Integrates physics and biology to understand molecular behaviors.

14: Scoring functions for docking – Discusses methods for evaluating molecular docking accuracy.

15: Protein structure database – Explores various databases used in protein structural research.

16: Biological data visualization – Introduces graphical techniques for analyzing molecular structures.

17: Computer Atlas of Surface Topography of Proteins – Maps protein surface features for functional insights.

18: Structure validation – Reviews methods to ensure accuracy in molecular modeling.

19: ITASSER – Details a leading tool for protein structure prediction.

20: Molecular Operating Environment – Examines a software suite for molecular modeling.

21: Genomics – Connects genetic information with structural bioinformatics.

This book is indispensable for those aiming to grasp the intricate details of biomolecular structures and their applications in medicine, biotechnology, and beyond. Whether you are a professional, student, or enthusiast, this book equips you with the knowledge and tools needed to excel in the evolving world of Molecular Biophysics.